Connection attempt failed with "ECONNREFUSED

Status: Connecting to ...
Status: Connection attempt failed with "ECONNREFUSED - Connection refused by server".
Error: Could not connect to server
Status: Waiting to retry...

Have you faced it before when using FileZilla? I just faced it just now.Previously, I get connected without problem but suddenly it happen.Stress, I google, some said due to antivirus some said due to firewall.So I open my MCAfee and try to uncheck something UNBLOCK like below and puff... the error goes away.